CD48 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human CD48.
Specificity	CD48 polyclonal antibody detects endogenous levels of CD48 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 48 kDa
Gene Name	CD48 molecule
Database Link	Entrez Gene 962 Human UniProt ID P09326
Background	CD48 is a glycosylphosphatidylinositol (GPI) -anchored membrane protein of the signaling lymphocyte activation molecule (SLAM) family, also known as SLAMF2 and BLAST-1. It is constitutively expressed on most hematopoietic cells (not on neutrophils and a subset of long-term hematopoietic stem cells in mice) and can be upregulated under certain conditions like infection. Interaction with its low affinity ligand CD2 promotes adhesion and TCR signaling. Interaction with the high affinity ligand CD244 (2B4) regulates natural killer (NK) and CD8 T cell activation and cytolytic function.
Synonyms	B-lymphocyte activation marker BLAST-1; BCM1; BCM1 surface antigen; BLAST1; CD48; CD48 antigen; CD_antigen: CD48; Leukocyte antigen MEM-102; Signaling lymphocytic activation molecule 2; SLAMF2; SLAM family member 2; TCT.1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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