Nectin 2 (NECTIN2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:2000~1:5000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human CD112/NECTIN2.
Specificity	CD112/NECTIN2 polyclonal antibody detects endogenous levels of CD112/NECTIN2 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 60-70 kDa
Gene Name	nectin cell adhesion molecule 2
Database Link	Entrez Gene 5819 Human UniProt ID Q92692
Background	Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive .Probable cell adhesion protein .
Synonyms	CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin-2; Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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