Calcineurin A (PPP3CA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB:1:2000~1:5000 IF: 1:50~1:200
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein.
Specificity	Calcineurin A polyclonal antibody detects endogenous levels of Calcineurin A protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 59 kD
Gene Name	protein phosphatase 3 catalytic subunit alpha
Database Link	Entrez Gene 5530 Human UniProt ID Q08209
Background	In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-Aα, PP2B-Aβ and PP2B-Aγ. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.
Synonyms	CALNA1; CAM-PRP catalytic subunit; CAM PRP catalytic subunit; CCN 1; CCN1; CNA; CNA1; CNA 1; CNA alpha; PP2BA; PPP2B; PPP3CA, Alpha isoform formerly PPP2B, Calcineurin A alpha, Calcineurin A1, CalcineurinA, Calmodulin dependent calcineurin A subunit alpha isoform, Calmodulin-dependent calcineurin A subunit alpha isoform, CALN, CALNA 1, CALNA; Ppp3ca, Protein phosphatase 2B catalytic subunit; Protein phosphatase 3 (formerly 2B) catalytic subunit alpha isoform; Protein phosphatase 3 catalytic subunit alpha isoform PPP3CA; Protein phosphatase 3 catalytic subunit alpha isozyme; Serine/threonine protein phosphatase 2B catalytic subunit alpha isoform
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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