TNFAIP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 90-140 of Human TNF-IP 1.
Specificity	TNF-IP 1 (S122) polyclonal antibody detects endogenous levels of TNF-IP 1 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 36 kDa
Gene Name	TNF alpha induced protein 1
Database Link	Entrez Gene 7126 Human UniProt ID Q13829
Background	TNFα-IP 1 (tumor necrosis factor, α-induced protein 1, endothelial), also known as B12, B61, EDP1 or TNFAIP1, is a BTB/POZ domain-containing protein that belongs to the KCTD10/KCTD13/TNFAIP1 family. TNFα-IP 1 contains one BTB/POZ motif, which is known to mediate homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. The expression of TNFα-IP 1 can be induced by IL-6 and by TNFα in the umbilical vein of endothelial cells. TNFα-IP 1 may be involved in DNA repair, DNA synthesis, cell apoptosis and human diseases. TNFα-IP 1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus.
Synonyms	BACURD2; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; EDP1; hBACURD2; Protein B12; TNFAIP1; Tumor necrosis factor, alpha-induced protein 1, endothelial
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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