Apolipoprotein L 2 (APOL2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 196-240of Human ApoL2.
Specificity	ApoL2 (R229) polyclonal antibody detects endogenous levels of ApoL2 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 37 kDa
Gene Name	apolipoprotein L2
Database Link	Entrez Gene 23780 Human UniProt ID Q9BQE5
Background	Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL 1-6, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.3 within a 127,000-bp region. ApoL2 and apoL3 may allow the binding of lipids to organ-elles or may be involved in the movement of lipids in the cytoplasm. ApoL2 localizes to the cytoplasm and is widely expressed, with the highest levels observed in the lung, thymus, pancreas, placenta, adult brain and prostate. The apoL2 protein is also detected in the spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver. ApoL3 also localizes to the cytoplasm and is widely expressed, with highest levels detected in the prostate, lung and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland. Lower levels of apoL3 are observed in the brain, heart, fetal liver, pancreas and testis.
Synonyms	ApoL-2; APOL2; Apolipoprotein L-2; Apolipoprotein L2
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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