Muscarinic Acetylcholine Receptor M4 (CHRM4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 241-290 of Human mAChR M4.
Specificity	mAChR M4 (P277) polyclonal antibody detects endogenous levels of mAChR M4 protein
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 53 kDa
Gene Name	cholinergic receptor muscarinic 4
Database Link	Entrez Gene 1132 Human UniProt ID P08173
Background	The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.
Synonyms	Muscarinic acetylcholine receptor M4,CHRM4
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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