hnRNP K (HNRNPK) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic phosphopeptide derived from human hnRNP K around the phosphorylation site of Serine 284
Specificity	p-hnRNP K (S284) pAb detects endogenous levels of hnRNP K protein only when phosphorylated at Ser284.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 58 to 62 kDa
Gene Name	heterogeneous nuclear ribonucleoprotein K
Database Link	Entrez Gene 3190 Human UniProt ID P61978
Background	The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K, a 65 kDa protein, recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.
Synonyms	Heterogeneous nuclear ribonucleoprotein K; HNRNPK; hnRNP K; HNRPK; Transformation up-regulated nuclear protein; TUNP
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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