Kmo Rabbit Polyclonal Antibody
CNY 8,025.00
货期*
4周
规格
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Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | WB: 1ug/ml ELISA: 1: 10,000 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Anti-KMO affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region surrounding 200-375aa of KMO protein. |
Specificity | Anti-KMO was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with mouse, rat, pig, and human based on 100% sequence homology. Cross-reactivity with KMO from other sources has not been determined. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | 1.0 mg/mL - lot specific |
Conjugation | Unconjugated |
Storage Condition | Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. |
Background | Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid is a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Anti-KMO antibodies are ideal for researchers interested in Apoptosis, Neurodegeneration, and Neuroscience research. |
Synonyms | rabbit anti-Kmo antibody, kynurenine 3-monooxygenase, kynurenine 3-hydroxylase |
Note | Anti-KMO antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~58kDa corresponding to the appropriate cell lysate or extract. |
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