NCR1 Rabbit Monoclonal Antibody [Clone ID: Bab281]

Specifications

Product Data
Clone Name	Bab281
Applications	FC, IF, IP
Reactivity	Human, Macaque
Modifications	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Host	Rabbit
Clonality	Monoclonal
Immunogen	The original antibody was generated by immunizing Balb/c mice with recombinant human NKp46 protein.
Specificity	The antibody is specific for human NKp46. The antibody cross-reacts with macaque NK46 but does not cross-react with mouse NKp46. NKp46 is a receptor expressed by NK cells. The antibody was used to immunoprecipitate NKp46 molecules from NK and COS-7 cells (Pessino et al., 1998; PMID 9730896 and Cantoni et al. 1999; PMID: 10049942). NK cells were analyzed for NKp46 surface expression by immunofluorescence and Flow Cytometry analysis using the antibody (Sivori et al., 1999; PMID: 10359120). The antibody binding to NKp46 promoted an increase of cytolytic activity in NK cells (Sivori et al., 1997; PMID: 9314561 and Sivori et al., 1999; PMID: 10359120).
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Database Link	UniProt ID O76036
Synonyms	CD335; hNKp46; Lymphocyte antigen 94 homolog; Natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; NK-p46; NK cell-activating receptor
Reference Data

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