Phospho-Ripk3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:1000
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around T231 & S232 of mouse RIP3 (NP_064339.2).
Formulation	Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	53kDa - Observed MW: 46-62kDa
Gene Name	receptor-interacting serine-threonine kinase 3
Database Link	Entrez Gene 56532 Mouse UniProt ID Q9QZL0
Background	Enables NF-kappaB-inducing kinase activity and protein serine/threonine kinase activity. Involved in several processes, including execution phase of necroptosis; hematopoietic or lymphoid organ development; and regulation of programmed cell death. Acts upstream of or within several processes, including I-kappaB kinase/NF-kappaB signaling; positive regulation of intrinsic apoptotic signaling pathway; and positive regulation of protein deacetylation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; hemolymphoid system gland; male reproductive gland or organ; primitive streak; and turbinate bone primordium. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3).
Synonyms	2610528K09Rik; Rip3
Reference Data

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