Vegfa Mouse Monoclonal Antibody [Clone ID: CH-10]

Specifications

Product Data
Clone Name	CH-10
Applications	WB
Reactivity	Rat, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant mouse VEGF.
Specificity	VEGF
Formulation	Phosphate buffered saline containing 0.1% Sodium Azide (NaN3) Label: Purified State: Purified IgG prepared by affinity chromatography from ascites Purified IgG - liquid
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	+4°C, -20°C if preferred
Gene Name	vascular endothelial growth factor A
Database Link	UniProt ID Q00731
Background	Mouse anti Mouse VEGF antibody, clone CH-10 recognises VEGF (vascular endothelial growth factor), a heparin-binding cytokine and member of the PDGF/VEGF growth factor family, which exists as several splice variants of the VEGF gene. VEGF, originally named vascular permeability factor due to its ability to act as vasodilator and increase microvascular permeability, is a potent stimulator of angiogenesis of both normal and cancerous cells, and acts as a regulator of vasculogenesis.The functional forms of VEGF exist as disulphide-linked homodimers and are classified according to the number of amino acid residues within a constitutive polypeptide chain e.g VEGF165. All VEGF family members act through binding to the tyrosine kinase receptors VEGFR-1 (Flt-1) and VEGFR-2 (KDR/CD309), whilst the closely-related VEGF-C and VEGF-D, can also bind to VEGFR-3 (Flt-4).
Synonyms	MGC70609; MVCD1; VEGF; VEGF-A; VPF
Reference Data

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