Aatf Rat Monoclonal Antibody [Clone ID: 1B2D8]

Specifications

Product Data
Clone Name	1B2D8
Applications	IF, WB
Reactivity	Human
Host	Rat
Clonality	Monoclonal
Immunogen	A peptide comprising amino acids 1-39 of mouse AATF (apoptosis-antagonizing transcription factor)
Specificity	AATF
Formulation	Phosphate buffered saline containing 0.035% Sodium Azide (NaN3)30% Glycerol Label: Purified State: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant Purified IgG - liquid
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	+4°C, -20°C if preferred
Gene Name	apoptosis antagonizing transcription factor
Database Link	UniProt ID Q9JKX4
Background	Rat anti Mouse AATF antibody, clone 1B2D8 recognizes apoptosis-antagonizing transcription factor, also known as Rb-binding protein che-1.AATF was first identified as an RNA pol II â€" interacting factor (Fanciulli et al. 2000). AATF is a protein encoded by the AATF gene. AATF mediates cellular responses and promotes cell proliferation and survival by inducing autophagy, DNA repair, and cell cycle arrest and inhibiting apoptosis (Kumar et al. 2019). DNA damage leads to phosphorylation of AATF at tyrosine 366 by the MAP kinase-activated protein kinase 2 (MK2) (Höpker et al. 2012).Rat anti Mouse AATF antibody detects a band of 80 kDa.
Synonyms	CHE-1; CHE1; DED
Reference Data

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