CDX2 Mouse Monoclonal Antibody [Clone ID: OTI1A3]

Specifications

Product Data
Clone Name	OTI1A3
Applications	IF, WB
Recommend Dilution	WB 1:1000
Reactivity	Human, Dog, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	33.5 kDa
Gene Name	caudal type homeobox 2
Database Link	NP_001256 Entrez Gene 12591 MouseEntrez Gene 66019 RatEntrez Gene 486028 DogEntrez Gene 1045 Human UniProt ID Q99626
Background	The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730)and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
Synonyms	CDX-3; CDX2/AS; CDX3
Reference Data
Protein Families	Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

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