MEK4 (MAP2K4) Mouse Monoclonal Antibody [Clone ID: OTI8A8]
CAT#: TA500403S
Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI8A8 (formerly 8A8)
Size: 100 ul
View other "OTI8A8" antibodies (4)
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CNY 800.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI8A8 |
Applications | FC, IF, IHC, IP, WB |
Recommend Dilution | WB 1:500~1000, IHC 1:150, IF 1:50~100, FLOW 1:100, IP 2ug/500ul |
Reactivity | Human, Dog, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full-length protein expressed in 293T cell transfected with human MAP2K4 expression vector |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 2.36 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 44.3 kDa |
Gene Name | mitogen-activated protein kinase kinase 4 |
Database Link | |
Background | This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver |
Synonyms | JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500403 | Carrier-free (BSA/glycerol-free) MAP2K4 mouse monoclonal antibody, clone OTI8A8 (formerly 8A8) |
CNY 3,999.00 |
|
TA500403 | Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI8A8 (formerly 8A8) |
CNY 1,999.00 |
|
TA500403AM | Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI8A8 (formerly 8A8), Biotinylated |
CNY 3,990.00 |
|
TA500403BM | Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI8A8 (formerly 8A8), HRP conjugated |
CNY 3,990.00 |