LAT2 (SLC7A8) Mouse Monoclonal Antibody [Clone ID: OTI5A9]
CAT#: TA500503
Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI5A9" antibodies (4)
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CNY 1,999.00
CNY 2,700.00
Cited in 1 publication. |
CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI5A9 |
Applications | FC, IF, IHC, IP, WB |
Recommend Dilution | WB 1:500, IHC 1:50, IF 1:100, FLOW 1:100, IP 2ug/500ul |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector . |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 58.4 kDa |
Gene Name | solute carrier family 7 member 8 |
Database Link | |
Background | Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney. |
Synonyms | LAT2; LPI-PC1 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma
,Cicone, F;Minniti, G;Oliva, MA;Carideo, L;Prior, JO;Scopinaro, F;Giangaspero, F;Arcella, A;,
Brain Tumor Pathol
,PubMed ID 28815339
[SLC7A8]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500503 | Carrier-free (BSA/glycerol-free) SLC7A8 mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) |
CNY 3,999.00 |
|
TA500503AM | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9), Biotinylated |
CNY 3,990.00 |
|
TA500503BM | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9), HRP conjugated |
CNY 3,990.00 |
|
TA500503S | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) |
CNY 800.00 |