LAT2 (SLC7A8) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7D6]

CAT#: TA500515AM

Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6), Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI7D6" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Transient overexpression lysate of solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (SLC7A8), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI7D6
Applications IHC, WB
Recommend Dilution WB: 1:200 - 1:1000, IHC 1:50
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 58.4 kDa
Gene Name solute carrier family 7 member 8
Background Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Synonyms LAT2; LPI-PC1
Reference Data
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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