FKBP51 (FKBP5) Mouse Monoclonal Antibody [Clone ID: OTI3E9]

Specifications

Product Data
Clone Name	OTI3E9
Applications	IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:50, IF 1:100
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human FKBP5 expression vector
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51.2 kDa
Gene Name	FKBP prolyl isomerase 5
Database Link	NP_004108 Entrez Gene 361810 RatEntrez Gene 2289 Human UniProt ID Q13451
Background	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Synonyms	AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10
Reference Data
Protein Families	Druggable Genome

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