TPMT Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5B4]

CAT#: TA500965BM

Anti-TPMT mouse monoclonal antibody, clone OTI5B4 (formerly 5B4), HRP conjugated

Conjugation: Unconjugated Biotin HRP



  View other "OTI5B4" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Recombinant protein of human thiopurine S-methyltransferase (TPMT), 20 µg
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Transient overexpression lysate of thiopurine S-methyltransferase (TPMT)
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Specifications

Product Data
Clone Name OTI5B4
Applications IHC, WB
Recommend Dilution WB 1:1000, IHC 1:50
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Condition Store at -20°C as received.
Predicted Protein Size 28.2 kDa
Gene Name thiopurine S-methyltransferase
Background This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Synonyms OTTHUMP00000016076; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; thiopurine S-methyltransferase
Reference Data
Protein Families Druggable Genome
Protein Pathways Drug metabolism - other enzymes
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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