Amyloid Precursor Protein (APP) Mouse Monoclonal Antibody [Clone ID: OTI2B10]
CAT#: TA500973
APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI2B10" antibodies (4)
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CNY 1,999.00
CNY 2,700.00
Cited in 1 publication. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
CNY 4,840.00
Specifications
Product Data | |
Clone Name | OTI2B10 |
Applications | IF, WB |
Recommend Dilution | WB 1:2000, IF 1:50 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human APP (NP_000475) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.74 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 87.0 kDa |
Gene Name | amyloid beta precursor protein |
Database Link | |
Background | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
Synonyms | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Alzheimer's disease |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Thioredoxin-1 Promotes Mitochondrial Biogenesis Through Regulating AMPK/Sirt1/PGC1α Pathway in Alzheimer's Disease
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ASN NEURO
,PubMed ID 36823760
[APP]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500973 | Carrier-free (BSA/glycerol-free) APP mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) |
CNY 3,999.00 |
|
TA500973AM | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10), Biotinylated |
CNY 3,990.00 |
|
TA500973BM | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10), HRP conjugated |
CNY 3,990.00 |
|
TA500973S | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) |
CNY 800.00 |
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