QPRT Mouse Monoclonal Antibody [Clone ID: OTI7A8]

Specifications

Product Data
Clone Name	OTI7A8
Applications	FC, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.64 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	30.6 kDa
Gene Name	quinolinate phosphoribosyltransferase
Database Link	NP_055113 Entrez Gene 23475 Human UniProt ID Q15274
Background	This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms	HEL-S-90n; QPRTase
Reference Data
Protein Pathways	Metabolic pathways, Nicotinate and nicotinamide metabolism

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