HDAC6 Mouse Monoclonal Antibody [Clone ID: OTI4C5]

Specifications

Product Data
Clone Name	OTI4C5
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:1000~2000, IF 1:100, FLOW 1:100, IHC 1:150
Reactivity	Human, Dog, Rat, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	131.2 kDa
Gene Name	histone deacetylase 6
Database Link	NP_006035 Entrez Gene 84581 RatEntrez Gene 480907 DogEntrez Gene 711363 MonkeyEntrez Gene 10013 Human UniProt ID Q9UBN7
Background	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq]
Synonyms	CPBHM; HD6; JM21; PPP1R90
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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