KEAP1 Mouse Monoclonal Antibody [Clone ID: OTI1B4]
CAT#: TA502059S
KEAP1 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4)
Size: 100 ul
View other "OTI1B4" antibodies (4)
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CNY 800.00
Cited in 3 publications. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI1B4 |
Applications | FC, IF, WB |
Recommend Dilution | WB 1:500~2000, FLOW 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinnt protein of human KEAP1(NP_987096) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 69.5 kDa |
Gene Name | kelch like ECH associated protein 1 |
Database Link | |
Background | This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq] |
Synonyms | INrf2; KLHL19 |
Reference Data | |
Protein Families | Transcription Factors |
Protein Pathways | Ubiquitin mediated proteolysis |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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Identification and Characterization of MCM3 as a Novel KEAP1 Substrate
,Mulvaney, KM;Matson, JP;Siesser, PF;Tamir, TY;Goldfarb, D;Jacobs, TM;Cloer, EW;Harrsion, JS;Vaziri, C;Cook, JG;Major, MB;,
J. Biol. Chem.
,PubMed ID 27621311
[KEAP1]
|
Bromodomain and Extraterminal Proteins Suppress NF-E2-Related Factor 2-Mediated Antioxidant Gene Expression
,Michaeloudes, C;Mercado, N;Clarke, C;Bhavsar, PK;Adcock, IM;Barnes, PJ;Chung, KF;,
J. Immunol. April 2014
,PubMed ID 24733848
[Keap1]
|
Activation of Transcription Factor Nrf2 Signalling by the Sphingosine Kinase Inhibitor SKI-II Is Mediated by the Formation of Keap1 Dimers
,Mercado, N;Kizawa, Y;Ueda, K;Xiong, Y;Kimura, G;Moses, A;Curtis, JM;Ito, K;Barnes, PJ;,
PLoS ONE, Feb 2014.
,PubMed ID 24505412
[Keap1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF502059 | Carrier-free (BSA/glycerol-free) KEAP1 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4) |
CNY 3,999.00 |
|
TA502059 | KEAP1 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4) |
CNY 1,999.00 |
|
TA502059AM | KEAP1 mouse monoclonal antibody,clone 1B4, Biotinylated |
CNY 3,990.00 |
|
TA502059BM | KEAP1 mouse monoclonal antibody,clone 1B4, HRP conjugated |
CNY 3,990.00 |