SOCS3 Mouse Monoclonal Antibody [Clone ID: OTI3D3]
CAT#: TA502991
SOCS3 mouse monoclonal antibody, clone OTI3D3 (formerly 3D3)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI3D3" antibodies (4)
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CNY 1,999.00
CNY 2,700.00
Cited in 3 publications. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 9,998.00
Specifications
Product Data | |
Clone Name | OTI3D3 |
Applications | FC, IF, IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 24.6 kDa |
Gene Name | suppressor of cytokine signaling 3 |
Database Link | |
Background | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq] |
Synonyms | ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Adipocytokine signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus, Ubiquitin mediated proteolysis |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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Association Between Circulating CD4 + T Cell Methylation Signatures of Network-Oriented SOCS3 Gene and Hemodynamics in Patients Suffering Pulmonary Arterial Hypertension
,null,
Journal of Cardiovascular Translational Research
,PubMed ID 35960497
[SOCS3]
|
Impact of PTEN/SOCS3 deletion on amelioration of dendritic shrinkage of retinal ganglion cells after optic nerve injury
,Mak, HK;Ng, SH;Ren, T;Ye, C;Leung, CKS;,
Exp. Eye Res.
,PubMed ID 31972211
[SOCS3]
|
Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation
,Lin, CR;Wei, TW;Tsai, HY;Wu, YT;Wu, PY;Chen, ST;,
FASEB J.
,PubMed ID 26296369
[SOCS3]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF502991 | Carrier-free (BSA/glycerol-free) SOCS3 mouse monoclonal antibody, clone OTI3D3 (formerly 3D3) |
CNY 3,999.00 |
|
TA502991AM | SOCS3 mouse monoclonal antibody, clone OTI3D3 (formerly 3D3), Biotinylated |
CNY 3,990.00 |
|
TA502991BM | SOCS3 mouse monoclonal antibody, clone OTI3D3 (formerly 3D3), HRP conjugated |
CNY 3,990.00 |
|
TA502991S | SOCS3 mouse monoclonal antibody, clone OTI3D3 (formerly 3D3) |
CNY 800.00 |