PTP1B (PTPN1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C5]
CAT#: TA503309BM
PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5), HRP conjugated
Conjugation: Unconjugated Biotin
View other "OTI1C5" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI1C5 |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PTPN1(NP_002818) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 49.8 kDa |
Gene Name | protein tyrosine phosphatase non-receptor type 1 |
Database Link | |
Background | The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. [provided by RefSeq] |
Synonyms | PTP1B |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase, Transmembrane |
Protein Pathways | Adherens junction, Insulin signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF503309 | Carrier-free (BSA/glycerol-free) PTPN1 mouse monoclonal antibody, clone OTI1C5 (formerly 1C5) |
CNY 3,999.00 |
|
TA503309 | PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5) |
CNY 1,999.00 |
|
TA503309AM | PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5), Biotinylated |
CNY 3,990.00 |
|
TA503309S | PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5) |
CNY 800.00 |