CCM2 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1D1]
CAT#: TA503419BM
CCM2 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1), HRP conjugated
Conjugation: Unconjugated Biotin
View other "OTI1D1" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI1D1 |
Applications | WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CCM2(NP_113631) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 48.7 kDa |
Gene Name | CCM2 scaffold protein |
Database Link | |
Background | This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms | C7orf22; OSM; PP10187 |
Reference Data |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF503419 | Carrier-free (BSA/glycerol-free) CCM2 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
CNY 3,999.00 |
|
TA503419 | CCM2 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
CNY 1,999.00 |
|
TA503419AM | CCM2 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1), Biotinylated |
CNY 3,990.00 |
|
TA503419S | CCM2 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
CNY 800.00 |