CCM2 Mouse Monoclonal Antibody [Clone ID: OTI4F5]

CAT#: TA503420S

CCM2 mouse monoclonal antibody, clone OTI4F5 (formerly 4F5)

Size: 30 ul 100 ul



  View other "OTI4F5" antibodies (4)

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【特别福利】购一抗正装产品(≥50ul或≥50ug),免费领10ul抗体试用装

CNY 800.00


货期*
现货

规格
    • 30 ul

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human cerebral cavernous malformation 2 (CCM2), transcript variant 2, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of cerebral cavernous malformation 2 (CCM2), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI4F5
Applications IF, WB
Recommend Dilution WB 1:2000, IF 1:100
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CCM2(NP_113631) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.77 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 48.7 kDa
Gene Name CCM2 scaffold protein
Background This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms C7orf22; OSM; PP10187
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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