NLN Mouse Monoclonal Antibody [Clone ID: OTI3A12]

Specifications

Product Data
Clone Name	OTI3A12
Applications	FC, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human NLN(NP_065777) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.94 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	80.5 kDa
Gene Name	neurolysin
Database Link	NP_065777 Entrez Gene 75805 MouseEntrez Gene 117041 RatEntrez Gene 57486 Human UniProt ID Q9BYT8
Background	This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
Synonyms	AGTBP; EP24.16; MEP; MOP
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Renin-angiotensin system

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