GIRK1 (KCNJ3) Mouse Monoclonal Antibody [Clone ID: OTI3E11]

Specifications

Product Data
Clone Name	OTI3E11
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 279-501 of human KCNJ3(NP_002230) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56.4 kDa
Gene Name	potassium inwardly rectifying channel subfamily J member 3
Database Link	NP_002230 Entrez Gene 16519 MouseEntrez Gene 50599 RatEntrez Gene 696473 MonkeyEntrez Gene 3760 Human UniProt ID P48549
Background	Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq]
Synonyms	GIRK1; KGA; KIR3.1
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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