Transferrin Receptor 2 (TFR2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1D8]

Specifications

Product Data
Clone Name	OTI1D8
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TFR2(NP_003218) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	88.6 kDa
Gene Name	transferrin receptor 2
Database Link	NP_003218 Entrez Gene 7036 Human UniProt ID Q9UP52
Background	This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Synonyms	HFE3; TFRC2
Reference Data
Protein Families	Druggable Genome, Protease, Transmembrane

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