PSMA2 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3B3]

Specifications

Product Data
Clone Name	OTI3B3
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:500
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 50-234 of human PSMA2(NP_002778) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25.7 kDa
Gene Name	proteasome 20S subunit alpha 2
Database Link	NP_002778 Entrez Gene 19166 MouseEntrez Gene 29669 RatEntrez Gene 475870 DogEntrez Gene 701683 MonkeyEntrez Gene 5683 Human UniProt ID P25787
Background	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]
Synonyms	HC3; MU; PMSA2; PSC2
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Proteasome

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