MEK3 (MAP2K3) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5F2]

CAT#: TA505646AM

MAP2K3 mouse monoclonal antibody,clone 5F2, Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI5F2" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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经常一起买 (3)
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Recombinant protein of human mitogen-activated protein kinase kinase 3 (MAP2K3), transcript variant B, 20 µg
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Transient overexpression lysate of mitogen-activated protein kinase kinase 3 (MAP2K3), transcript variant B
    • 100 ug

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Specifications

Product Data
Clone Name OTI5F2
Applications IF, IHC, WB
Recommend Dilution WB 1:200~2000, IHC 1:150, IF 1:100
Reactivity Human, Dog, Rat, Monkey, Mouse
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MAP2K3(NP_659731) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 39.1 kDa
Gene Name mitogen-activated protein kinase kinase 3
Background The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
Synonyms MAPKK3; MEK3; MKK3; PRKMK3; SAPKK-2; SAPKK2
Reference Data
Protein Families Druggable Genome, Protein Kinase, Transcription Factors
Protein Pathways Amyotrophic lateral sclerosis (ALS), Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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