IDO1 Mouse Monoclonal Antibody [Clone ID: OTI1A3]
CAT#: TA506402
IDO1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3)
Size: 30 ul
Formulation: Carrier-Free
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CNY 1,999.00
CNY 2,700.00
Cited in 2 publications. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
Product Data | |
Clone Name | OTI1A3 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:4000, IHC 1:150, IF 1:100 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human IDO1(NP_002155) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 45.1 kDa |
Gene Name | indoleamine 2,3-dioxygenase 1 |
Database Link | |
Background | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. [provided by RefSeq, Feb 2011] |
Synonyms | IDO; IDO-1; INDO |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Tryptophan metabolism |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells
,Jonescheit, H;Oberg, HH;Gonnermann, D;Hermes, M;Sulaj, V;Peters, C;Kabelitz, D;Wesch, D;,
Cells
,PubMed ID 32384638
[IDO1]
|
The immunology of the macaque placenta: A detailed analysis and critical comparison with the human placenta
,Buse, E;Markert, UR;,
Crit Rev Clin Lab Sci
,PubMed ID 30632863
[IDO1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF506402 | Carrier-free (BSA/glycerol-free) IDO1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) |
CNY 3,999.00 |
|
TA506402AM | IDO1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3), Biotinylated |
CNY 3,990.00 |
|
TA506402BM | IDO1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3), HRP conjugated |
CNY 3,990.00 |
|
TA506402S | IDO1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) |
CNY 800.00 |