PCNA Rabbit Polyclonal Antibody
CNY 5,302.00
Cited in 1 publication. |
CNY 3,080.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 9,998.00
Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommend Dilution | WB 1:5000~20000, IHC 1:150, ELISA 1:100-1:2000 |
Reactivity | Human, Dog, Rat, Monkey, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | DNA immunization. This antibody is specific for the Middle Region of the target protein. |
Formulation | 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 |
Concentration | 0.9mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | proliferating cell nuclear antigen |
Database Link | |
Background | PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
Synonyms | ATLD2 |
Note | This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
---|
Impact of Glutathione Peroxidase-1 Deficiency on Macrophage Foam Cell Formation and Proliferation: Implications for Atherogenesis
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PLoS ONE
,PubMed ID 23991041
[PCNA]
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