KEAP1 Rabbit Polyclonal Antibody

CAT#: TA590238

Rabbit Polyclonal KEAP1 Antibody



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CNY 5,302.00


货期*
4周

规格
    • 100 ug

经常一起买 (5)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1
    • 100 ug

CNY 3,080.00


Recombinant protein of human kelch-like ECH-associated protein 1 (KEAP1), transcript variant 2, 100 µg
    • 100 ug

CNY 9,998.00


Transient overexpression lysate of kelch-like ECH-associated protein 1 (KEAP1), transcript variant 2
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications ELISA, IHC, WB
Recommend Dilution WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen DNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Formulation 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 0.9mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name kelch like ECH associated protein 1
Background KEAP1 retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Synonyms INrf2; KLHL19
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Transcription Factors
Protein Pathways Ubiquitin mediated proteolysis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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