Growth hormone receptor (GHR) Rabbit Polyclonal Antibody
CAT#: TA590807
Rabbit Polyclonal Growth hormone receptor Antibody
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CNY 5,302.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | ELISA |
Recommend Dilution | WB: 1:5000-1:20000; ELISA: 1:100-1:2000 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | DNA immunization. This antibody is specific for the Middle Region of the target protein. |
Formulation | 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 |
Concentration | 0.96mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | growth hormone receptor |
Database Link | |
Background | This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized. |
Synonyms | GHBP; GHIP |
Note | This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction |
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