EVI1 (MECOM) Rabbit Polyclonal Antibody
CNY 5,302.00
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CNY 300.00
CNY 1,430.00
CNY 4,840.00
Specifications
Product Data | |
Recommend Dilution | WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | DNA immunization. This antibody was made against a protein fragment from the N Terminus Region |
Formulation | 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 |
Concentration | 0.87372 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | MDS1 and EVI1 complex locus |
Database Link | |
Background | EVI1 (ecotropic viral integration site 1) was originally identified as a gene located in the integration site of ecotropic retroviruses in the mouse genome that resulted in myeloid tumors. EVI1 is a zinc finger transcription factor that plays an important role in development and leukemogenesis. It is an oncogene that can have effects on cell proliferation, differentiation, and apoptosis. Chromosomal translocations involving EVI1 result in chronic myelogenous leukemia (CML). Alternate names for EVI1 include AML1-EVI-1 fusion protein, PRDM3, and MDS1-EV1. |
Synonyms | AML1-EVI-1; EVI1; MDS1; MDS1-EVI1; PRDM3 |
Note | This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Chronic myeloid leukemia, MAPK signaling pathway, Pathways in cancer |
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