glucose 6 phosphatase, catalytic subunit (G6PC) Rabbit Monoclonal Antibody [Clone ID: OTIR4H3]
CAT#: TA592779
G6PC Rabbit monoclonal antibody,clone OTIR4H3
Size: 30 ul
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CNY 1,999.00
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CNY 300.00
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Specifications
Product Data | |
Clone Name | OTIR4H3 |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:200-1:1000 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human G6PC (NP_000142). The exact sequence is proprietary. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
Predicted Protein Size | 40.5 kDa |
Gene Name | glucose-6-phosphatase catalytic subunit 1 |
Database Link | |
Background | Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011] |
Synonyms | G6Pase; G6PC; G6PT; GSD1; GSD1a |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Adipocytokine signaling pathway, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA592779S | G6PC Rabbit monoclonal antibody,clone OTIR4H3 |
CNY 870.00 |
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