mIgLC Rabbit Monoclonal Antibody [Clone ID: OTIR3F7]

CAT#: TA594080S

mIgLC Rabbit monoclonal antibody, clone OTIR3F7

Size: 30 ul 100 ul



  View other "OTIR3F7" antibodies (1)

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【特别福利】购一抗正装产品(≥50ul或≥50ug),免费领10ul抗体试用装

CNY 870.00


货期*
现货

规格
    • 30 ul

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经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00

Specifications

Product Data
Clone Name OTIR3F7
Applications ELISA
Recommend Dilution ELISA 1:5000-10000
Reactivity Mouse
Host Rabbit
Clonality Monoclonal
Immunogen Native protein
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size 25 kDa
Background Immunoglobulin G (IgG) is the predominant antibody class present in mouse and human serum. It is also the main class used in development of antibody therapies, especially those for cancer.1 IgG is also used to treat immune defificiencies and auto-immune diseases in the form of intravenous immunoglobulin (IVIg), generated from a plasma pool of thousands of donors.Human IgG can be divided in 4 subclasses, IgG1, IgG2, IgG3 and IgG4, and mouse in IgG1, IgG2a, IgG2b and IgG3, with IgG2c being the equivalent of IgG2a in some mouse strains such as C47Bl/6 mice. All subclasses mediate effector functions slightly different due to variable specificity and affinity for the different IgG binding partners mentioned above. Most of the currently approved therapeutic monoclonal antibodies are IgG1, but also IgG2 and IgG4 are used. IgG2 and IgG4 are preferred when Fc-mediated effector functions are not needed or not preferred, as these subclasses bind with lower affinity to the FcgR and activate complement less actively.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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