Myeloperoxidase (MPO) Mouse Monoclonal Capture Antibody [Clone ID: OTI4G10]

CAT#: TA600575

MPO mouse monoclonal antibody, clone OTI4G10



  View other "OTI4G10" antibodies (3)

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CNY 2,600.00

CNY 4,250.00


货期*
2周

规格
    • 100 ul

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经常一起买 (1)
MPO biotinylated mouse monoclonal antibody, clone OTI4B1
    • 100 ul

CNY 2,600.00
CNY 4,250.00

Specifications

Product Data
Clone Name OTI4G10
Applications ELISA
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length recombinant protein of human MPO (NP_000241) produced in Baculovirus-Insect cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Predicted Protein Size 83.7 kDa
Gene Name myeloperoxidase
Background Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene. MPO protein is a 150-kDa cationic heterotetramer consisting of two 15-kDa light chains and two variable-weight glycosylated heavy chains bound to a prosthetic heme group, arranged as a homodimer of heterodimers. MPO is most abundantly expressed in neutrophil granulocytes, and produces hypohalous acids to carry out their antimicrobial activity, including hypochlorous acid. It is a lysosomal protein stored in azurophilic granules of the neutrophil and released into the extracellular space during degranulation. Myeloperoxidase deficiency is a hereditary deficiency of the enzyme, which predisposes to immune deficiency. Recent studies have reported an association between elevated myeloperoxidase levels and the severity of coronary artery disease, and elevated MPO levels increased the risk for cardiovascular mortality. It has also been suggested that myeloperoxidase plays a significant role in the development of the atherosclerotic lesion and rendering plaques unstable. MPO could serve as a sensitive predictor for myocardial infarction.
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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