MAGEA3 Biotinylated Mouse Monoclonal Detection Antibody (Biotin conjugated) [Clone ID: OTI24B6]

Specifications

Product Data
Clone Name	OTI24B6
Applications	ELISA
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MAGEA3 (NP_005353) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Predicted Protein Size	34.6 kDa
Gene Name	MAGE family member A3
Database Link	NP_005353 Entrez Gene 4102 Human UniProt ID P43357
Background	Human Cancer/testis antigen MAGEA3 is a member of Melanoma Antigen Gene (MAGE) family, which has restricted expression to the testis and is aberrantly expressed in cancer cells. MAGEA3 has been found to be broadly expressed in a variety of malignancies such as melanoma, breast cancer, head and neck cancer, lung cancer, gastric cancer, skin squamous cell carcinoma, prostate cancer, colorectal cancer, etc.  It has been shown that MAGEA3 expression is associated with cancer progression and metastasis, and increased expression of MAGE-A3 in cancer cells is associated with poor prognosis of cancer patients.
Synonyms	CT1.3; HIP8; HYPD; MAGE3; MAGEA6
Reference Data

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