UBE2E3 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6D3]

Specifications

Product Data
Clone Name	OTI6D3
Applications	FC, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human UBE2E3 (NP_006348) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22.7 kDa
Gene Name	ubiquitin conjugating enzyme E2 E3
Database Link	NP_006348 Entrez Gene 22193 MouseEntrez Gene 295686 RatEntrez Gene 10477 Human UniProt ID Q969T4
Background	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Synonyms	UBCH9; UbcM2
Reference Data
Protein Pathways	Ubiquitin mediated proteolysis

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