TRIF (TICAM1) Mouse Monoclonal Antibody [Clone ID: OTI1G7]

Specifications

Product Data
Clone Name	OTI1G7
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 120-420 of human TICAM1 (NP_891549) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	76.2 kDa
Gene Name	toll like receptor adaptor molecule 1
Database Link	NP_891549 Entrez Gene 574294 MonkeyEntrez Gene 148022 Human UniProt ID Q8IUC6
Background	This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012]
Synonyms	IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Toll-like receptor signaling pathway

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