ALK Rat Monoclonal Antibody [Clone ID: OTI5F4]
CAT#: TA801031S
ALK rat monoclonal antibody, clone OTI5F4 (formerly 5F4)
Size: 100 ul
View other "OTI5F4" antibodies (4)
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CNY 800.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 4,840.00
Specifications
Product Data | |
Clone Name | OTI5F4 |
Applications | WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Rat |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1300-1620 of human ALK (NP_004295)produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 176.3 kDa |
Gene Name | anaplastic lymphoma receptor tyrosine kinase |
Database Link | |
Background | This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). [provided by RefSeq, Jan 2011] |
Synonyms | CD246; NBLST3 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF801031 | Carrier-free (BSA/glycerol-free) ALK rat monoclonal antibody, clone OTI5F4 (formerly 5F4) |
CNY 3,999.00 |
|
TA801031 | ALK rat monoclonal antibody, clone OTI5F4 (formerly 5F4) |
CNY 1,999.00 |
|
TA801031AM | ALK rat monoclonal antibody,clone 5F4, Biotinylated |
CNY 3,990.00 |
|
TA801031BM | ALK rat monoclonal antibody,clone 5F4, HRP conjugated |
CNY 3,990.00 |