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PTEN Mouse Monoclonal Antibody [Clone ID: OTI1C3]
CAT＃: TA801053S
PTEN mouse monoclonal antibody, clone OTI1C3 (formerly 1C3)
Size: 100 ul
View other "OTI1C3" antibodies (4)
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CNY 800.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Clone Name | OTI1C3 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PTEN (NP_000305) produced in SF9 Cell. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 47 kDa |
| Database Link | |
| Background | This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. [provided by RefSeq, Jul 2008] |
| Synonyms | 10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1 |
| Reference Data | |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | Endometrial cancer, Focal adhesion, Glioma, Inositol phosphate metabolism, Melanoma, p53 signaling pathway, Pathways in cancer, Phosphatidylinositol signaling system, Prostate cancer, Small cell lung cancer, Tight junction |
Documents
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| 抗体相关资料 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| CF801053 | Carrier-free (BSA/glycerol-free) PTEN mouse monoclonal antibody, clone OTI1C3 (formerly 1C3) |
CNY 4,418.00 |
|
| TA801053 | PTEN mouse monoclonal antibody, clone OTI1C3 (formerly 1C3) |
CNY 1,999.00 |
|
| TA801053AM | PTEN mouse monoclonal antibody,clone 1C3, Biotinylated |
CNY 3,990.00 |
|
| TA801053BM | PTEN mouse monoclonal antibody,clone 1C3, HRP conjugated |
CNY 3,990.00 |
