ALK Mouse Monoclonal Antibody [Clone ID: OTI1A4]
CAT#: TA801287
ALK mouse monoclonal antibody, clone OTI1A4 (discontinued and upgraded to UltraMAB UM800118)
View other "OTI1A4" antibodies (7)
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CNY 1,999.00
CNY 2,700.00
Cited in 6 publications. |
CNY 4,840.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 9,998.00
Specifications
Product Data | |
Clone Name | OTI1A4 |
Applications | IHC, LMNX, WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1300-1620 of human ALK (NP_004295) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 176.3 kDa |
Gene Name | anaplastic lymphoma receptor tyrosine kinase |
Database Link | |
Background | This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). [provided by RefSeq, Jan 2011] |
Synonyms | CD246; NBLST3 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Citations (6)
The use of this Antibodies has been cited in the following citations: |
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Cerebellar Morphology and Behavioral Profiles in Mice Lacking Heparan Sulfate Ndst Gene Function
,Lewejohann, L;Pallerla, SR;Schreiber, RS;Gerula, J;Grobe, K;,
J Dev Biol
,PubMed ID 32664575
[ALK]
|
Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma
,Du, X;Gao, Y;Zhao, H;Li, B;Xue, W;Wang, D;,
Oncol Lett
,PubMed ID 29805657
[ALK]
|
Anaplastic lymphoma kinase immunohistochemistry in lung adenocarcinomas: Evaluation of performance of standard manual method using D5F3 antibody
,Jain, D;Jangra, K;Malik, PS;Arulselvi, S;Madan, K;Mathur, S;Sharma, MC;,
Indian J Cancer
,PubMed ID 29199692
[ALK]
|
Inflammatory myofibroblastic tumour of the bladder in children: A review
,Collin, M;Charles, A;Barker, A;Khosa, J;Samnakay, N;,
J Pediatr Urol
,PubMed ID 25982020
[ALK]
|
A Novel, Highly Sensitive ALK Antibody 1A4 Facilitates Effective Screening for ALK Rearrangements in Lung Adenocarcinomas by Standard Immunohistochemistry
,Gruber K, Kohlhäufl M, Friedel G, Ott G, Kalla C.,
J Thorac Oncol. 2015 Apr;10(4):713-6
,PubMed ID 25789835
[ALK]
|
Extraordinary response to crizotinib in a woman with squamous cell lung cancer after two courses of failed chemotherapy
,Wang, Q;He, Y;Yang, X;Wang, Y;Xiao, H;,
BMC Pulm Med
,PubMed ID 24885608
[ALK]
[Human; IHC] |
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抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF801287 | Carrier-free (BSA/glycerol-free) ALK mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) |
CNY 3,999.00 |
|
TA801287AM | ALK mouse monoclonal antibody,clone 1A4, Biotinylated |
CNY 3,990.00 |
|
TA801287BM | ALK mouse monoclonal antibody,clone 1A4, HRP conjugated |
CNY 3,990.00 |
|
TA801287S | ALK mouse monoclonal antibody, clone OTI1A4 (discontinued and upgraded to UltraMAB UM800118) |
CNY 800.00 |
|
UM800118 | ALK (CD246)mouse monoclonal antibody, clone OTI1A4 |
CNY 2,999.00 |
|
UM800118CF | Carrier-free (BSA/glycerol-free) ALK mouse monoclonal antibody, clone OTI1A4 |
CNY 4,999.00 |
|
UM870118 | ALK mouse monoclonal antibody, clone OTI1A4 |
CNY 1,150.00 |