DOCK8 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1E11]

Specifications

Product Data
Clone Name	OTI1E11
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 84-405 of human DOCK8 (NP_982272) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	238.3 kDa
Gene Name	dedicator of cytokinesis 8
Database Link	NP_982272 Entrez Gene 76088 MouseEntrez Gene 499337 RatEntrez Gene 81704 Human UniProt ID Q8NF50
Background	This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Synonyms	HEL-205; MRD2; ZIR8
Reference Data

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