FGFR1 Mouse Monoclonal Antibody [Clone ID: OTI3C4]
CAT#: TA802987
FGFR1 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4)
Size: 30 ul
Formulation: Carrier-Free
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CNY 1,999.00
CNY 2,700.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 9,998.00
Specifications
Product Data | |
Clone Name | OTI3C4 |
Applications | WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-376 of human FGFR1 (NP_075598)produced in SF9 cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 89.4 kDa |
Gene Name | fibroblast growth factor receptor 1 |
Database Link | |
Background | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
Synonyms | bFGF-R-1; BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | Adherens junction, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF802987 | Carrier-free (BSA/glycerol-free) FGFR1 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4) |
CNY 3,999.00 |
|
TA802987AM | FGFR1 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4), Biotinylated |
CNY 3,990.00 |
|
TA802987BM | FGFR1 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4), HRP conjugated |
CNY 3,990.00 |
|
TA802987S | FGFR1 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4) |
CNY 800.00 |