Fos B (FOSB) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5D5]

Specifications

Product Data
Clone Name	OTI5D5
Applications	IHC, WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-255 of human FOSB (NP_006723) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	FosB proto-oncogene, AP-1 transcription factor subunit
Database Link	NP_006723 Entrez Gene 14282 MouseEntrez Gene 2354 Human UniProt ID P53539
Background	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	AP-1; G0S3; GOS3; GOSB
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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