XRCC3 Mouse Monoclonal Antibody [Clone ID: OTI5B11]

Specifications

Product Data
Clone Name	OTI5B11
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-235 of human XRCC3 (NP_005423) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	37.7 kDa
Gene Name	X-ray repair complementing defective repair in Chinese hamster cells 3
Database Link	NP_005423 Entrez Gene 7517 Human UniProt ID O43542
Background	This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Synonyms	CMM6
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Homologous recombination

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