PARP1 Mouse Monoclonal Antibody [Clone ID: OTI5F1]
CAT#: TA804938S
PARP1 mouse monoclonal antibody, clone OTI5F1 (formerly 5F1)
Size: 100 ul
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CNY 800.00
Cited in 3 publications. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
Product Data | |
Clone Name | OTI5F1 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PARP1 (NP_001609) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 112.9 kDa |
Gene Name | poly(ADP-ribose) polymerase 1 |
Database Link | |
Background | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008] |
Synonyms | ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Base excision repair |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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An ellagic acid isolated from Clerodendrum viscosum leaves ameliorates iron-overload induced hepatotoxicity in Swiss albino mice through inhibition of oxidative stress and the apoptotic pathway
,Shendge, AK;Basu, T;Panja, S;Chaudhuri, D;Mandal, N;,
Biomed. Pharmacother.
,PubMed ID 29990833
[PARP1]
|
Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura
,Milillo, A;Molinario, C;Costanzi, S;Vischini, G;La Carpia, F;La Greca, F;Rigante, D;Gambaro, G;Gurrieri, F;Sangiorgi, E;,
J. Nephrol.
,PubMed ID 29497996
[PARP1]
|
A natural antioxidant, tannic acid mitigates iron-overload induced hepatotoxicity in Swiss albino mice through ROS regulation
,Basu, T;Panja, S;Shendge, AK;Das, A;Mandal, N;,
Environ. Toxicol.
,PubMed ID 29446234
[PARP1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF804938 | Carrier-free (BSA/glycerol-free) PARP1 mouse monoclonal antibody, clone OTI5F1 (formerly 5F1) |
CNY 3,999.00 |
|
TA804938 | PARP1 mouse monoclonal antibody, clone OTI5F1 (formerly 5F1) |
CNY 1,999.00 |
|
TA804938AM | PARP1 mouse monoclonal antibody, clone OTI5F1 (formerly 5F1), Biotinylated |
CNY 3,990.00 |
|
TA804938BM | PARP1 mouse monoclonal antibody, clone OTI5F1 (formerly 5F1), HRP conjugated |
CNY 3,990.00 |